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Semaglutide (Ozempic/Wegovy) Primary uses: Weight loss Appetite suppression Type 2 diabetes management Cardiovascular health Typical dosing: Week 1-4: 0.25mg once weekly Week 5-8: 0.5mg once weekly Week 9-12: 1mg once weekly Week 13-16: 1.7mg once weekly Week 17+: 2.4mg once weekly (max) Administration: Subcutaneous injection, once weekly Special notes: FDA-approved for obesity Most effective weight loss peptide Dramatic appetite suppression Common side effects: nausea, constipation See our semaglutide vs tirzepatide guide and use our semaglutide dosage calculator
It's important to note that semaglutide carries a boxed warning for thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
Chen W, Qin H, Zhou Z, Chen Y, Xu X, Chen Y, He J, Xu R, Gao H, Lu Q
People with a history of certain eye problems, like diabetic retinopathy or recent changes in vision, should discuss risks with their provider before starting semaglutide, as these conditions may get worse
Sulser, F., Vetulani, J
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