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Samples of blood and stimulated whole saliva were collected from fasted participants in the morning hours between 8:00 AM and 10:00 AM for the further analyses

By amplifying ROS and starting other harmful reactions, hypoxia throws off this equilibrium and damages tissue

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The study of La Rubia et al

Clinical trials Although several studies using in vitro and in vivo experimental models have reported the protective effects of polyphenols in CFS and muscle atrophies, human use is still scarce in this area, perhaps due to ambiguities in polyphenol bioavailability, doses, and lack of efficacy in humans (Nikawa et al