These arent hard contraindications, but theyre situations where extra caution makes sense
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Stability: Lyophilized form remains stable when stored under recommended conditions
Furthermore, the role of luminal microbes in SLE development is reinforced by the fact that patients express the LTA receptor, TLR2, in greater abundance when compared to healthy controls, and the removal of commensal microbes via antibiotic treatment can ameliorate disease symptoms (Liu et al