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Moreover, patients with acromegaly treated with either GH-receptor antagonists or somatostatin analogues represent a peculiar setting that need to be studied in depth to define safety and efficacy of both drug classes and their interaction with the GH/IGF-1 axis

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According to comprehensive weight loss plateau GLP-1 research, about one-third of non-diabetic patients on GLP-1s achieve 10% weight loss, but progress typically stalls after 2024 weeks

This leaves the nerves themselves more susceptible to injury, which leads to the odd range of sensations we described above