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Cigarette smoking can cause citrullination (a post-translation modification of the amino acid arginine) of proteins in the body which results in the production of anticyclic citrullinated protein antibodies that are strongly associated with the development of RA

Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD

[DOI] [PubMed] [Google Scholar] 95.Wijarnpreecha K, Werlang M, Panjawatanan P, Pungpapong S, Lukens FJ, Harnois DM, et al

(2017) 27:R98894