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Sleep apnea, a condition where breathing stops and restarts intermittently throughout sleep, has been associated with infertility in both men and women

Rybelsus is officially the first oral GLP-1 drug approved for this indication

In these populations, GLP-1 medications may: Suppress appetite in ways that destabilize recovery Mask symptoms without addressing underlying drivers Increase psychological distress related to food, weight, or control Any consideration of GLP-1 use should involve careful medical oversight, psychological evaluation, and ongoing monitoring

Thirst is blunted, so patients don't instinctively drink more

Importantly, the first step in heme biosynthesis requires the amino acid glycine, the production of which is NRF2 regulated