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Modern medicine already shows how powerful these small molecules can become when researchers test them carefully.

Patients were 63-year-old and only 15% had a baseline history of cardiovascular disease

Multiple RCTs used 4% topical HQ as an active ingredient in combination therapies or comparison arms, but most of the literature on 4% HQ as a therapeutic modality was published before 2003

On the other hand, a vitamin B12 deficiency appears to cause a loss of appetite in some people, leading to weight loss rather than weight gain ( That said, the current evidence is too weak to suggest that a vitamin B12 deficiency has any strong or specific impact on weight be it weight gain or loss