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The 2530 nmol/kg figure was chosen early and repeated, never optimized

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Riazi, H., Tehranian, N., Ziaei, S., Mohammadi, E., Hajizadeh, E., & Montazeri, A

CJC-1295 and Somatotroph Biology The GHRH-receptor signalling pathway activated by CJC-1295 stimulates adenylate cyclase, increasing intracellular cAMP and engaging PKA-linked transcriptional regulation of the GH gene in somatotroph cells with in vivo research confirming increased pituitary RNA, GH mRNA, and somatotroph cell number following administration, establishing that GHRH-class secretagogues act on multiple levels of GH axis biology beyond simple acute secretion