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Glycemic mechanism and insulin sparing sensitization not secretion: fasting insulin and C-peptide fall while insulin sensitivity (HOMA2-%S) rises +31.8/+43.2/+49.9% (SURPASS J-mono, Hamamoto 2025)

[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Vogel H., Wolf S., Rabasa C., Rodriguez-Pacheco F., Babaei C.S., Stber F., Goldschmidt J., DiMarchi R.D., Finan B., Tschp M.H., et al

Despite considerable focus on intracellular GSH synthesis and membrane transport 29,30 , the mechanisms governing mitochondrial GSH import remain poorly understood

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The role of adipokines in inflammatory mechanisms of obesity