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For example, when investigating the hypothesis that gap junctions transport toxic metabolites to neighboring cells and support their killing during APAP and thioacetamide hepatotoxicity, the fact that the new gap junction inhibitor 2-aminoethoxydipenyl-borate (2APB) protected against the injury appeared to support the hypothesis [154]

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Sekhar, Siripoom V

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For use only after a single, acute ingestion in a patient who has not recently taken acetaminophen prior to ingestion