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This nuclear localization in elderly Leydig cells correlated with reduced expression of 3-HSD, a crucial enzyme for testosterone synthesis, suggesting a link between nuclear FOXO4 and age-related decline in testosterone production [2]

Neuroprotective effects of morroniside from Cornus officinalis sieb

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However, how AMPK regulates GLP-1 signalling pathway needs to be further investigated

Indeed, the mutant molecule we engineered, HPV-16 E7 Mut, while unable to bind 6-His-GSTP1 in vitro as a recombinant protein, displayed a certain residual effectiveness in vivo in binding native GSTP1, in safeguarding it from oxidation and in protecting the cells from UV-induced cell death