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A bias factor ( ), which quantifies the relative engagement of one signalling state over another compared with the reference peptide, was calculated using the following equation: Where E max is the maximal effect, EC 50 is the half maximal concentration of the peptide, lig is the peptide being tested (P5 or GLP-1)

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Exogenous pigmentations are usually associated with traumatic or iatrogenic events resulting in the deposition of foreign material directly into the mucosal tissues (Table 52)

Kapoor, G., Saigal, S

Going from 40% to 7.5% represents a transformation from moderate hair loss to near-normal coverage