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Given the relative concentrations of different ROS, the battery of H 2 O 2 -metabolizing enzymes potentially linked to glutathione, and the marked changes in glutathione status when other H 2 O 2 -metabolizing enzymes such as catalase are down-regulated, the main focus of the following discussion concerns the enzymes that could be important in linking H 2 O 2 or related peroxides to GSH oxidation to GSSG

PK shown for the DAC form, extrapolated to no-DAC

In Satyanarayana, T, Deshmukh S, Johri B (eds) Developments in fungal biology and applied mycology

Oxidative stress may cause damages to lipids, proteins, and DNAs in cells, with subsequent disease development in humans 13

Technical replicates and biological replicates (n) used for all experiments are described in the figure legends