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Athough increase in liver size as measured by liver weight is correlated with microsomal enzyme induction, neither the degree or extent of hypertrophy nor the magnitude of the weight increase is correlated with the magnitude of the enzyme induction in rats, dogs, or monkeys (Amacher et al

*Correspondence: Neda Roshanravan, [email protected] Dehghan, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Based on the current level of evidence, other authors have also suggested the use of oral or topical glutathione as an adjunctive therapy for facial melanosis

Understanding the relationship between these two conditions is important for patients with fatty liver disease, as vitamin B12 deficiency can lead to serious complications including anaemia, neurological damage, and cognitive impairment