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Energy The production of the coenzyme Q10 and carnitine depends on methylation (19, 20)

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By contrast, the upregulation of ACSL4, ALOX15, and NCOA4 promotes lipid peroxidation and intracellular iron accumulation, exacerbating cell death (42-45)

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Despite the limited biosynthesis capability of the RBC, some endogenous GSH is still synthetized in the cytosol through two ATP-dependent reactions catalyzed by two different enzymes, glutamate cysteine ligase and glutathione synthase [13]

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2008 Therrien G, Rose C, Butterworth J, Butterworth RF: Protective effect of L-carnitine in ammonia-precipitated encephalopathy in the portacaval shunted rat

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