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In preclinical models of arthritis, CS12192 has been reported to ameliorate the disease severity and bone destruction, along with immunomodulatory effects such as the suppression of CD4 + T cell activation and reduction in pro-inflammatory cytokine production (114)

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Compounding pharmacies prepare these medications individually under state pharmacy board oversight and applicable federal requirements - but that process is fundamentally different from the manufacturing and regulatory review applied to brand-name FDA-approved medications

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