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Despite its importance, few is known about actors involved in human gut barrier function, since most of the data are limited to animal studies which have shown that microbiota changes can promote disruption of intestinal barrier homeostasis [37]

Interpretation is limited by species-specific physiology, controlled dosing protocols, and experimental environments that differ from complex endocrine regulation in broader biological systems

It consists of three amino acids glycine, cysteine, and glutamine and affects a wide range of cellular processes

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