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[97] In contrast to generics, which may be chemically synthesized versions manufactured using different processes than the original biologic drug, Health Canada confirmed that Plosbrio and Poviztra differ from the existing proprietary drugs Ozempic and Wegovy only in name and packaging, and are unrelated to the generics from a regulatory perspective

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In conclusion, lactate plays a key role in the tumor immunosuppressive microenvironment and the mechanisms by which high lactate levels affect immune cells through Kla warrant further investigation