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Common side effects are typically mild and temporary: Injection site reactions (redness, slight bruising) Mild headaches (usually first week only) Temporary fatigue as your body adjusts Serious side effects are rare when protocols are followed correctly

[1] [2] Patients should be monitored for serious adverse effects including: Thyroid tumors (boxed warning): Report symptoms such as neck mass, dysphagia, dyspnea, or persistent hoarseness Pancreatitis: Discontinue if suspected

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Winfrey, who at her heaviest weighed 237 pounds, said she no longer obsesses over food