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investigates the potential role of GLP-1RAs as DMARDs in 1807 patients with knee OA and T2DM

Oral supplementation with a combination of L-citrulline and L-arginine rapidly increases plasma L-arginine concentration and enhances NO bioavailability

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Microglia instead maintain ramified processes along with a single, small, ill-defined circular process at the glial limitans (white arrowhead)

Consistent with these pathological findings, both semaglutide and tirzepatide significantly lowered liver triglycerides (TG) and total cholesterol (TC) (Fig.4-C, D)